The National Implant Biocompatibility and Longitudinal Health Surveillance Initiative: Genetic Susceptibility, Dynamic Immune Profiling, Device Integrity Monitoring, and the Long-Term Scientific Value of Medical Data
The National Implant Biocompatibility and Longitudinal Health Surveillance Initiative Genetic Susceptibility, Dynamic Immune Profiling, Device Integrity Monitoring, and the Long-Term Scientific Value of Medical Data John Swygert November 11, 2026 DOI: To be assigned Abstract This paper proposes a federally funded national infrastructure for standardized, longitudinal collection of clinical, device-specific, genetic, and immunological data associated with implanted medical devices, with eventual expansion to selected procedures. Its scientific value does not depend on demonstrating that implants cause any particular illness. Patients’ symptoms and biological states change over time; therefore, one-time symptomatic/asymptomatic labels are inadequate. The proposed framework integrates mandatory device and procedure reporting, consent-based biospecimen collection, repeated outcomes assessment, carefully governed research access, and optional investigation of miniature wireless integrity se...